EFFECT OF TOPICAL APPLICATION OF TRANEXAMIC ACID ON WOUND DRAINAGE POST MODIFIED RADICAL MASTECTOMY

EFFECT OF TOPICAL APPLICATION OF TRANEXAMIC ACID ON WOUND DRAINAGE POST MODIFIED RADICAL MASTECTOMY

Objective: To compare efficacy of topical tranexamic acid versus standard postop care in reducing wound drainage following modified radical mastectomy (MRM).

Study Design: Randomized controlled trial. Setting and Duration: Department of General Surgery, Gulab Devi Hospital, over period of six months.

Methods: Total of 60 patients undergoing MRM were enrolled and randomly allocated into two groups, with 30 patients in each group. Group I received topical tranexamic acid applied to surgical wound, while Group II received standard postop care without tranexamic acid. Objective was to assess total wound drainage ( in ml), duration of drainage (in days) and frequency of wound infection among two group. Data were analyzed using SPSS version 26, and p-value ≤0.05 was considered statistically significant.

Inclusion Criteria:

1. All patients diagnosed with ductal or lobular breast carcinoma for whom MRM is indicated.

Exclusion Criteria:

1. History of thromboembolic events.
2. Patients with coagulation disorders.
3. Currently on anticoagulant therapy.