R-GASTIM- Study of Gastric Cancer Operable

R-GASTIM - Clinicobiological Cohort of Gastric Cancers

Clinicobiological cohort of gastric cancers operated in our institution.

Study of microenvironment of gastric cancers using tumor and lymph nodes, collected as per standard of care. Analysis by RNASeq and HyperIon

Inclusion Criteria:

• Adult patients with histologically proven non-metastatic resectable gastric and gastroesophageal junction adenocarcinoma, Stage IB to III be treated with standard neoadjuvant chemotherapy
• Knwon response to neoadjuvant chemotherapy as per TRG criteria
• Surgery of primary tumor done at Centre Léon Bérard. Availability of archival FFPE tumor block from initial diagnosis with at least 20% of tumor cells and collected lymp nodes

Exclusion Criteria:

• Patient refusal to participate to this clinicobiological cohort