The Effects of Carnitine Supplementation on Oocytes in Women Undergoing IVF Process

Participants will:

• Be women undergoing IVF treatment at the Narodni Front Clinic of Gynecology and Obstetrics who meet the study eligibility criteria and agree to participate.
• Be randomly assigned, using the sealed-envelope method, to one of two groups:
• A supplementation group receiving L-arginine (500 mg), L-carnitine (500 mg), N-acetyl-L-carnitine (250 mg), and myo-inositol (1000 mg) daily.
• A control group receiving no supplementation.
• Take the assigned supplementation for 12 weeks before oocyte retrieval.
• Undergo assessment of the number and quality of retrieved oocytes after oocyte aspiration as part of the standard IVF procedure.
• If fertilization occurs and embryos are obtained, have the number and quality of embryos evaluated as part of the standard IVF procedure.
• Have serum beta-human chorionic gonadotropin (β-hCG) measured 13 days after embryo transfer to assess biochemical pregnancy as part of the standard IVF procedure.
• If biochemical pregnancy is achieved (β-hCG > 50 IU/L), undergo an ultrasound examination 35 days after embryo transfer to confirm clinical pregnancy as part of the standard IVF procedure.