Comparison of Transversus Abdominis Plane and Erector Spinae Plane Blocks for Pain Control After Renal Laparoscopy | NCT07781930 | Trialant

RecruitingInterventionalNot ApplicableUpdated Aug 24, 2026

Comparison of Transversus Abdominis Plane and Erector Spinae Plane Blocks for Pain Control After Renal Laparoscopy

Comparison of Ultrasound-guided Transversus Abdominis Plane Block (TAP) and Erector Spinae Plane Block (ESPB) for Postoperative Analgesia in Adult Laparoscopic Renal Surgeries: A Randomized Controlled Trial.

Overview

Key facts that identify this study and show where it stands today.

ClinicalTrials.gov ID: NCT07781930
Lead Sponsor: Cairo UniversityOTHER
Overall Status: Recruiting
Study Type: Interventional
Phase: Not Applicable
Enrollment: 60Estimated
Last Update Posted: Aug 24, 2026Actual
Start Date: Jan 5, 2026Actual
Primary Completion Date: Aug 2026Estimated
Completion Date: Aug 2026Estimated

Description

What the study is about and why it is being run, in the researchers' own words.

Official Title: Comparison of Ultrasound-guided Transversus Abdominis Plane Block (TAP) and Erector Spinae Plane Block (ESPB) for Postoperative Analgesia in Adult Laparoscopic Renal Surgeries: A Randomized Controlled Trial.
Brief Summary: The goal of this study is to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries. Forty adults (18-60 years, ASA I-II) will be randomly assigned to receive either TAP or ESPB after induction of general anesthesia. Postoperative pain will be assessed using the Visual Analogue Scale (VAS) and total fentanyl consumption over 24 hours. Secondary outcomes include time to first analgesic request, hemodynamic parameters, patient satisfaction, and incidence of complications. The study will be conducted at Cairo University Hospitals following ethical approval, with all patients providing written informed consent.

Conditions

The medical conditions and diseases this study investigates.

Postoperative Pain, Acute

Interventions

The treatments and procedures being evaluated in this study.

TAP Block

Participation

Who can join this study and the criteria used to decide.

Ages Eligible for Study: Adult (18-64)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Eligibility Criteria: Inclusion criteria:

Age from 18 to 40 years old.

Both sexes.

American Society of Anesthesiology (ASA) physical status I, II.

Scheduled for laparoscopic renal surgeries under general anesthesia

Exclusion criteria:

Parent's refusal.

Coagulation disorders.

History of allergy to local anesthetics.

Infection or redness at the injection site.

History of renal and/or hepatic insufficiency.

Preexisting cardiac dysfunction.

Design

How the study is designed and how its participant groups are organized.

Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Double

Contacts

The people to reach with questions about this study or how to join it.

Hala ElSabbagh, M.D.Contact

halaelsabbagh@gmail.com01005207896

Locations

Where the study is run and whether each site is currently recruiting.

Kasr Al-Ainy hospitalRecruiting

Cairo, 11562, Egypt

Collaborators

The organizations and people involved in this study.

Lead Sponsor: Cairo UniversityOTHER

Similar Studies

Other registered studies that closely resemble this one.

This randomized controlled trial aims to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries. Forty adults (18-60 years, ASA I-II) will be randomly assigned to receive either TAP or ESPB after induction of general anesthesia.

Preoperative assessment will include medical and surgical history, clinical examination, and routine laboratory investigations.

Intraoperative management will follow standard monitoring with general anesthesia, and the block will be performed under ultrasound guidance using 0.25% bupivacaine, bilaterally. TAP block will be performed at the anterolateral abdominal wall, while ESPB will be performed at the T8-T9 level in lateral decubitus position. The anesthesiologist performing the block will not participate in postoperative data collection, and outcome assessors will be blinded.

Postoperative pain management includes IV paracetamol every 8 hours and rescue fentanyl boluses (25 μg IV) if VAS ≥4, with a maximum total dose of 0.2-0.4 mg in 24 hours. Pain will be measured using the Visual Analogue Scale (VAS) at PACU, 2, 4, 6, 12, 18, and 24 hours. Secondary outcomes include time to first analgesic request, hemodynamic parameters, patient satisfaction, and incidence of adverse events such as PONV, hypotension, bradycardia, urinary retention, LAST, pneumothorax, or failed block.

Primary outcome: total fentanyl consumption in the first 24 hours postoperatively.

Secondary outcomes: time to first rescue analgesia, VAS scores, hemodynamic stability, patient satisfaction, and complications. The study will be conducted at Cairo University Hospitals after ethical committee approval, with all patients providing written informed consent. Data will be analyzed using SPSS v26, with parametric and non-parametric tests, repeated-measures ANOVA for VAS over time, Kaplan-Meier analysis for time to rescue analgesia, and chi-square or Fisher's exact test for categorical outcomes.