Skin Staples vs Polypropylene in Elective Laparotomy

Skin Staples Versus Polypropylene for Skin Closure in Elective Laparotomy: A Randomized Controlled Trial

Overview

Key facts that identify this study and show where it stands today.

What the study is about and why it is being run, in the researchers' own words.

Official Title: Skin Staples Versus Polypropylene for Skin Closure in Elective Laparotomy: A Randomized Controlled Trial
Brief Summary: Surgical site infection (SSI) is one of the most common postoperative complications following elective laparotomy and contributes significantly to patient morbidity, prolonged hospital stay, and increased healthcare costs. Various techniques are available for skin closure, including skin staples and polypropylene sutures; however, evidence regarding their comparative effectiveness remains inconsistent, particularly in low- and middle-income countries.

This randomized controlled trial aims to compare skin staples with polypropylene sutures for skin closure following elective laparotomy. Eligible adult patients undergoing elective laparotomy at the Department of General Surgery, Pakistan Institute of Medical Sciences (PIMS), Islamabad, will be randomly allocated in a 1:1 ratio to receive either skin staples or polypropylene sutures.

The primary outcomes are skin closure time and incidence of surgical site infection within 30 days of surgery. Secondary outcomes include wound dehiscence, postoperative pain, cosmetic scar appearance, patient satisfaction, and duration of hospital stay.

The findings will provide evidence regarding the optimal skin closure technique for elective laparotomy in the Pakistani population.

The medical conditions and diseases this study investigates.

The treatments and procedures being evaluated in this study.

Who can join this study and the criteria used to decide.

Ages Eligible for Study: Child (0-17)Adult (18-64)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes
Eligibility Criteria: Inclusion Criteria:

Age 15-50 years Elective laparotomy ASA I-III Written informed consent Male or female

Exclusion Criteria:

Emergency surgery Previous SSI Recurrent surgery BMI <18 or >30 kg/m² Haemoglobin <10 g/dL COPD Stroke Renal failure Liver disease Haematological disorders Malignancy Immunocompromised state Active infection Previous chemotherapy Previous radiotherapy Malnutrition

How the study is designed and how its participant groups are organized.

The people to reach with questions about this study or how to join it.

No central contacts

There are no central contacts for this study.

Where the study is run and whether each site is currently recruiting.

Pakistan Institute of Medical SciencesRecruiting

Islamabad, Capital, Pakistan

The organizations and people involved in this study.

Other registered studies that closely resemble this one.