Novel Irrigation Solution for Colonoscopy Visualization Pilot

A Pilot Evaluation of a Novel Irrigation Solution to Enhance Visualization During Colonoscopy

The purpose of this study is to assess the provider experience with a novel colonoscopy irrigation solution and determine the feasibility of introducing this solution into the endoscopy unit and assess efficacy on a small scale prior to a larger study. Specifically, the study will assess mucosal visibility, colonic spasm, and intralumenal bubbles observed during colonoscopy.

Patient Inclusion Criteria:

1. Between 45 to 75 years of age
2. Currently receiving gastroenterology or primary care at NYU Langone Hospital
3. Capacity and willingness to provide consent
4. Undergoing a screening colonoscopy

Provider Inclusion Criteria:

1. Faculty gastroenterologist at NYU Langone Ambulatory Care Center
2. At least 18 years of age
3. Willingness to provide consent

Patient Exclusion Criteria:

1. Under 45 years or over 75 years of age
2. Known allergy to blue dye, peppermint and/or simethicone
3. Current use of antispasmodics or anti-flatulance agents
4. Pregnancy: This exclusion is based on standard clinical practice and safety considerations, as colonoscopy is not typically performed during pregnancy except in urgent circumstances. Accordingly, inclusion of pregnant individuals in this elective, pilot feasibility study would not be clinically appropriate or scientifically justified.

Provider Exclusion Criteria:

1. Not a gastroenterology provider at NYULH