Not yet recruitingInterventionalPhase 4Last updated Aug 13, 2026

Anti-inflammatory Effect of MgSO₄ in Patients With Moderate Traumatic Brain Injury by Measurming Nucleotide-binding Oligomerization Domain-Like Receptor Pyrin Domain-containing 3 (NLRP3) Inflammasome-a Multiprotein Complex

Anti-Inflammatory Effect of Magnesium Sulfate on the Outcomes of Patients With Moderate Traumatic Brain Injury.

Overview

ClinicalTrials.gov ID: NCT07763665
Lead Sponsor: Assiut UniversityOTHER
Brief Summary: The primary objective of this study is to evaluate the biochemical efficacy of Magnesium Sulfate (MgSO₄) as an anti-inflammatory therapeutic agent in patients suffering from moderate traumatic brain injury (TBI) at Assiut University Hospitals by measuring Nucleotide-binding oligomerization domain-Like Receptor Pyrin domain-containing 3 (NLRP3) inflammasome-a multiprotein complex.
Study Type

Status

Study Record Dates

NCT04646876Completed

Mgso4 as Neuroprotective in Post Traumatic Brain Injury

NCT00004730Completed

Magnesium Sulfate For Brain Injury

NCT07252505Not yet recruiting

Early Intravenous Magnesium Sulfate and Its Impact on Cerebral Vasospasm in Traumatic Subarachnoid Hemorrhage

NCT01333488Terminated

Mild Hypothermia and Supplemental Magnesium Sulfate Infusion in Severe Traumatic Brain Injury (TBI) Subjects

NCT03475693Completed

A Cohort Study Evaluating the Efficacy of PO Magnesium in the Treatment of Acute Traumatic Brain Injury in Adolescents

NCT04166877Recruiting

Magnesium Infusion for Pain Management in Critically Ill Trauma Patients