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Able to stand or sit with support on a WBV platform
Children able to follow simple verbal commands
Children with no visual or auditory defects
Parental/legal guardian consent obtained
Attending regular therapy sessions at the study site

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Children with uncontrolled epilepsy and cerebral palsy
Severe musculoskeletal or orthopedic impairments
Presence of implanted medical devices (e.g., pacemaker)
Any recent surgery (<6 months)
Children currently undergoing another experimental therapy

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While core symptoms often receive priority in diagnosis and intervention, motor coordination difficulties and sensory integration challenges-present in a significant proportion of autistic children- remain underexplored. Research shows that up to 83% of children with ASD struggle with age-appropriate motor skills, and sensory processing abnormalities further hinder their participation in daily routines. Traditional therapies, although beneficial, often fail to address these interconnected domains comprehensively. Whole-body vibration (WBV) therapy, a non-invasive physical intervention that stimulates neuromuscular function through low frequency vibrations, has shown promise in improving motor control, coordination, and even behavioral outcomes in various clinical populations, including children with cerebral palsy and Down syndrome. However, its application in pediatric ASD, particularly for sensory and motor integration, remains limited in empirical evidence. This randomized controlled trial aims to evaluate the efficacy of low-frequency Whole Body Vibration therapy on motor skills and sensory integration in children aged 3-10 years diagnosed with mild to moderate ASD. The study will be conducted over 10 months at two pediatric rehabilitation centers in Pakistan and will involve 36 participants divided into intervention and control groups. The intervention group will receive low-frequency Whole Body Vibration sessions combined with routine physiotherapy, while the control group will engage in routine physical activity. Motor skills will be assessed using the Test of Gross Motor Development-2 (TGMD-2), and sensory processing will be evaluated with the Short Sensory Profile. The vibration protocol includes 3-4 rounds of 30-second sessions with rest intervals, using a platform set at 28 Hz and 0.97 mm amplitude. 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A 1min rest interval will be provided between each vibration period. Upon completion of each session, the participant will be taken immediately to the observation room. A 5-minute post-session observation period will be conducted to monitor behavioral or physiological response Each participant will undergo between 10 and 40 individual sessions, depending on their tolerance and the requirement for data stability.","interventionNames":["Other: whole body vibration"]},{"label":"Routine physical therapy group","type":"OTHER","description":"10 min session per day. 5 session per week. 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Treatment patterns in children with autism in the United States. Autism Res. 2019 Mar;12(3):517-526. doi: 10.1002/aur.2070. Epub 2019 Jan 10."}]},"ipdSharingStatementModule":{"ipdSharing":"NO"}},"derivedSection":{"miscInfoModule":{"versionHolder":"2026-08-13"},"conditionBrowseModule":{"meshes":[{"id":"D000067877","term":"Autism Spectrum Disorder"},{"id":"D001321","term":"Autistic Disorder"}],"ancestors":[{"id":"D002659","term":"Child Development Disorders, Pervasive"},{"id":"D065886","term":"Neurodevelopmental Disorders"},{"id":"D001523","term":"Mental Disorders"}]}},"hasResults":false}}]}]