The aim of this study is to investigate the potential roles of PGRMC1, PGRMC2, and PAQR family membrane progesterone receptors in the pathophysiology of gestational diabetes mellitus by comparing their expression levels in placentas from pregnancies complicated by gestational diabetes mellitus with those from healthy pregnancies.
Inclusion Criteria: Healthy women with singleton pregnancies 18-45 years pregnant gestational diabetes mellitus -
Exclusion Criteria: Multiple pregnancies pregnant women under the age of 18 or over the age of 45
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Control Group
Gestational diabetes mellitusGroupPregnant women diagnosed with gestational diabetes who will undergo placental tissue collection at delivery for molecularanalysis. Healthy Control GroupHealthy pregnant women with normal oral glucose tolerence test result who will undergo placental tissue collection at delivery for molecular analysis.
Samsun, Turkey (Türkiye)
Construction and Biological Study of Blood and Placenta Samples Associated With Gestational Diabetes Mellitus
Possible Epigenetic Changes in Offspring of Women With Pregestational and Gestational Diabetes
Gestational Diabetes Mellitus: "Placental-maternal Crosstalk and Future Health"
Impact of Blood Glucose at the First Trimester of Pregnant Women With Gestational Diabetes on Maternal and Fetal Outcomes and Metabolic Disorders: a Multi-central Prospective Cohort Study
Long Term Effects of Gestational Diabetes Mellitus in a Population of Parous Women