Impact of Antioxidant-rich Supplementation on Skin Carotenoids Status, Antioxidant Status and Cardiometabolic Health in Overweight and Obese... | NCT07748468

NCT07748468

Overview

NCT ID: NCT07748468
Lead Sponsor: National University of SingaporeOTHER
Official Title: Impact of Antioxidant-rich Supplementation on Skin Carotenoids Status, Antioxidant Status and Cardiometabolic Health in Overweight and Obese Individuals
Brief Summary: This study aims to evaluate the effects of antioxidant-rich supplementation on skin carotenoid status, antioxidant status, and cardiometabolic health in overweight and obese individuals. The study may provide additional scientific evidence to support the further refinement of current dietary and nutritional recommendations.
Conditions: Overweight , Obesity
Antioxidant Status
Interventions

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Aug 5, 2026Actual
Start Date: Aug 15, 2026Estimated
Primary Completion Date: Aug 1, 2027Estimated

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion Criteria:

Able to give informed consent (AMT score ≥ 8 for older adults [65-70 years old])

Adults 21-70 years old

English-literate

Have venous access sufficient to allow for blood sampling as per the protocol

No drastic change of diet for the past 1 year

If taking medication, has been consistently taking antihypertensive/cholesterol-lowering/type-2 diabetic medication for more than 3 years prior to starting the study

Exclusion Criteria:

Weight change > 3kg in the past 3 months

Exercising vigorously over the past 3 months

Taking medications or dietary supplements which may impact eye/skin health

Taking lipid-lowering and blood pressure controlling medications less than 3 years

Smoking

Drinking more than 2 alcoholic drinks per day

Pregnant, lactating, or planning pregnancy in the next 6 months

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 83Estimated
Primary Purpose: Prevention
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking

Contacts and Locations

Central Contacts: Lingyin Yu, B.Sc.Contact
e1124962@u.nus.edu

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