Background: Female university students in Ethiopia experience a high burden of sexual and reproductive health, nutrition, and psychosocial problems, exacerbated by limited access to essential health services and support. Mobile technology provides an opportunity to deliver accessible, evidence-based health interventions.

Objective: To evaluate the effectiveness of a mobile technology-based intervention in improving SRH, nutrition, and psychosocial well-being among female university students in Ethiopia.

Methods: A concurrent mixed-methods study will be conducted among first-year female university students. Baseline quantitative and qualitative assessments will identify needs, barriers, and facilitators. A randomized controlled trial will evaluate a comprehensive mobile health education intervention delivered monthly. Quantitative data will be analysed using descriptive and inferential statistics, while qualitative data will undergo thematic analysis.

Expected Outcomes: Improved sexual and reproductive health, dietary practices, and psychosocial well-being among female university students.

Duration and Budget: The project will be implemented over the proposed study period with a total budget of 1,208,564 Ethiopian birr.