Network Modeling in Knee Osteoarthritis | NCT07746284

NCT07746284

Overview

NCT ID: NCT07746284
Lead Sponsor: George Mason UniversityOTHER
Official Title: Network Modeling in Knee Osteoarthritis
Brief Summary: This project seeks to understand inter-individual differences in chronic musculoskeletal pain (cMSKP). Our long-term objective is to develop clinically-feasible decision tools that enable whole-person assessment and management of cMSKP and guide personalized primary, secondary and tertiary prevention strategies. Our secondary objective is to understand how inter-relationships between physiological, biomechanical and psychosocial factors change over time and impact the experience of living with chronic pain.
Conditions: Chronic Musculoskeletal Pain
Interventions

Status and Timeline

Status: Enrolling by invitation
Last Update Posted: Aug 5, 2026Actual
Start Date: Mar 13, 2026Actual
Primary Completion Date: Jul 31, 2029Estimated

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion criteria:

Adults aged 18-years old or more

Chronic pain for 3 months or more around the knee joint.

Exclusion criteria:

Acute pain due to knee injury or surgery within the past 3 months.

Diagnosis of lumbar radiculopathy, neuropathy or neuritis.

Special populations i. Adults unable to consent ii. Pregnant women (self-reported) iii. Prisoners iv. George Mason University Athletes

Military

Bleeding disorders, blood thinners, recent blood transfusions, vasovagal syncope, and current infection.

Study Plan

Study Type: Observational
Phase: No data available
Enrollment: 200Estimated
Primary Purpose: No data available
Allocation: No data available
Interventional Model: No data available
Masking

Contacts and Locations

Central Contacts: No data available
Locations: Optimal Motion Physical Therapy

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