Analgesic Effects of Retro-superior Costotransverse Ligament Space Block for Video-assisted Thoracoscopic Surgery | NCT07745881

NCT07745881

Overview

NCT ID: NCT07745881
Lead Sponsor: Nanjing First Hospital, Nanjing Medical UniversityOTHER
Official Title: Postoperative Analgesic Effects of Ultrasound-guided Retro-superior Costotransverse Ligament Space Block After Video-assisted Thoracoscopic Surgery: a Prospective Randomized Controlled Trial
Brief Summary: The aim of this clinical trial is to investigate the effects of postoperative analgesia during retro-SCTLB(retro superior costotransverse ligament space block) and TPVB(thoracic paravertebral block) in patients undergoing thoracoscopic radical resection of lung cancer。By comparing the dosage of opioid drugs after surgery, the impact of retro-SCTLB and TPVB on the postoperative analgesic effect was evaluated.
Conditions: Nerve Block
Thoracoscopic Radical Resection of Lung Cancer

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Aug 4, 2026Actual
Start Date: Aug 31, 2026Estimated
Primary Completion Date: May 20, 2028Estimated

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Patients scheduled for thoracoscopic radical lung cancer surgery under general anesthesia；(1)aged 18-80 years； (2) BMI 18-30 kg/m²；(3)ASA classification I-III

Exclusion Criteria:

(1)Allergy to the study drug or local anesthetic; (2) History of opioid abuse; (3) Pre-existing skin infection at the puncture site of ITPN or TPVB; (4) Peripheral infectious neuropathy; (5) Dysfunction of blood coagulation

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 130Estimated
Primary Purpose: Prevention
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking

Contacts and Locations

Central Contacts: Tao ShanContact
shantao2021@163.com

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retro-SCTLB groupExperimental

A total of 20 ml of the 0.375% ropivacaine is injected in the retro-superior costotransverse ligament space in the retro-SCTLB group。

Procedure: Ultrasound-guided retro-SCTLB

TPVB groupExperimental

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