Novel Abdominal Compression Positioning Technique for Respiratory Motion Management in Liver Tumors | NCT07745153

NCT07745153

Overview

NCT ID: NCT07745153
Lead Sponsor: Southern Medical University, ChinaOTHER
Official Title: Novel Abdominal Compression Positioning Technique for Respiratory Motion Management in Liver Tumors
Brief Summary: Research Background The background of this study centers on stereotactic body radiation therapy (SBRT), an advanced form of radiotherapy that is short in duration, highly effective, and easy for patients to comply with. However, even small breathing movements can reduce its precision. Abdominal compression devices have been proven to reduce respiratory motion and are now widely used in clinical practice. This study aims to determine whether a novel abdominal compression positioning technique can control tumor motion as effectively as current abdominal compression devices, whether it works better than traditional thermoplastic masks, and whether it can offer meaningful benefits to patients undergoing radiotherapy. These questions remain to be explored.

Study Objectives The purpose of this study is to investigate how different immobilization devices affect the respiratory motion of liver tumors, in order to better assist with target delineation and the delivery of stereotactic body radiation therapy.

Status and Timeline

Status: Completed
Last Update Posted: Aug 4, 2026Actual
Start Date: Jan 1, 2025Actual
Primary Completion Date: Jul 23, 2026Actual
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Voluntarily signed informed consent.

Age ≥ 18 years.

Patients who require radiotherapy for liver cancer, as determined by the treating physician.

Life expectancy > 3 months.

Exclusion Criteria:

Discontinuation of radiotherapy or failure to complete the radiotherapy plan as prescribed.

Presence of serious complications or comorbidities that may affect safety.

Study Plan

Study Type: Observational
Phase: No data available
Enrollment: 120Actual
Primary Purpose: No data available
Allocation: No data available
Interventional Model: No data available
Masking

Contacts and Locations

Central Contacts: No data available
Locations: Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China

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Part of the Modern Art Study