Early Pregnancy Cohort Inclusion Criteria

• 18 years of age
• Gestational age at enrollment: Between 12.0 and 13.6 weeks of gestation
• Pregnant individuals receiving care at participating clinical sites with intent of delivering at study hospital
• Consent to participate in study procedures through 6 weeks postpartum

Late Pregnancy Cohort

• 18 years or older
• Gestational age at enrollment: greater than or equal to 28.0 weeks gestational age
• Clinical indications of risk FGR <10th percentile or report of decreased fetal movement)
• Pregnant individual receiving care at participating clinical sites with intent of delivering at study hospital
• Consent to participate in study procedures through 6 weeks postpartum

Exclusion Criteria:

• Evidence of fetal genetic anomaly or major structural malformation
• Known fetal aneuploidy based on chorionic villus sampling
• Positive cell-free fetal DNA screening for aneuploidy
• Multifetal gestation
• Less than 18 years of age
• Not fluent in either English or Spanish