We have observed that the serum levels of certain metabolites differ between Chilean patients with gallbladder cancer and those with gallstone disease. Based on these discovery results, we selected ten candidate metabolites based on the smallest p-values among metabolites exhibiting a fold-change greater than 1.5. The aim of the present study is to validate these ten differential metabolite levels in an independent cohort of Chilean patients with gallbladder cancer and gallstone disease, and to assess the transferability of these findings to other patient populations.
Inclusion Criteria:
Exclusion Criteria:
• Patients younger than 18 years
Cochabamba, Bolivia
Validation of Differential Serum Levels for Five Minerals in South American Gallstone Patients With and Without Gallbladder Cancer
Validation of the Association Between the Abundance of Three Bacterial Genera in Stool Samples and the Risk of Gallbladder Cancer in South American Patients With Gallstones
Validation of the Proteomic Profiling as a Diagnostic Test for Extra-hepatic Cholangiocarcinoma