Inclusion Criteria:

• ≥18 years

• Symptomatic fluid collection following a left pancreatectomy requiring drainage according to the treatment team. Indications for drainage exists of:

  1. Symptoms of abdominal pain and/or persistent nausea.
  2. Suspected infection/ sepsis

• Drainage of the fluid collection is feasible both endoscopically and percutaneously as per the treating team. NB: Preferably this is also assessed and supported by the expert panel, but this is NOT mandatory given the potential urgent nature of the intervention. The investigators expect that multidisciplinary consultation with both intervening specialties precedes the feasibility assessment.

• No contraindications for either procedure. If the contraindication can be overcome safely, such as ascites for which prior abdominal drainage is needed, the patient can still be included.

• No prior drainage attempts of the fluid collection.

• In case of a previously intraoperatively placed drain, it should have been removed 5 days prior to fluid collection development.

Exclusion Criteria:

• <18 years
• The fluid collection is not endoscopically or percutaneously feasible per the expert panel's judgement or the treatment team in acute situations, for example due to collection location too far from the gastrointestinal tract.
• Prior drainage attempts of the fluid collection.
• Received an indwelling percutaneous drain intraoperatively. Intraoperatively placed drains are only permitted when at least removed 5 days prior to development of the fluid collection.
• Permanent incapacitation of research participant, prior to clinical deterioration caused by the pancreatic fluid collection, without expectation of improvement as per the treatment team.
• Unable to obtain informed consent by either patient or their legal representative.