Inclusion Criteria:

1. Adult participant (18 - 39 years old)
2. Body mass index (BMI) 18 - 30 kg/m2
3. At least moderate intensity aerobic exercise ≥60 min per week
4. Participant is able and willing to follow study procedures

Exclusion Criteria:

1. History of cardiovascular, neurological, metabolic, pulmonary, renal, gastrointestinal, or autoimmune disease
2. Taking prescription medication (with exception of psychiatric medication)
3. If taking a psychiatric medication, the dosage has changed within the month prior to first study visit
4. Cannot abstain from taking over-the-counter medications or supplements for 24 hours before study visits (with exception of vitamins)
5. Resting systolic blood pressure ≥130 mmHg and/or diastolic blood pressure ≥90 mmHg
6. Resting heart rate of ≥100 beats per minute
7. Regular smoker of cigarettes or has regularly smoked in the past year
8. Musculoskeletal injury/condition that negatively impacts the protocol
9. History of heat illness that resulted in a visit to a medical center in the past 2 years
10. Has donated blood or plasma in the past 3 months
11. Has taken antibiotics or corticosteroids within 4 weeks of enrollment
12. Has a medical implant device such as a pacemaker, patient monitoring system, or metallic implant
13. Has a full or partially amputated limb
14. Pregnant or breastfeeding
15. Study physician or PI discretion based on any other medical condition or medication