A Randomized, Assessor-Blinded, Intraindividual Study on the Efficacy of Fractional Carbon Dioxide Laser Versus Long-Pulsed 1064 nm Nd:YAG Laser... | NCT07739420

NCT07739420

Overview

NCT ID: NCT07739420
Lead Sponsor: Jose R. Reyes Memorial Medical CenterOTHER_GOV
Official Title: A Randomized, Assessor-Blinded, Intraindividual Study on the Efficacy of Fractional Carbon Dioxide Laser Versus Long-Pulsed 1064 nm Nd:YAG Laser in the Treatment of Keratosis Pilaris
Brief Summary: This study compares the efficacy of fractional carbon dioxide laser versus long-pulsed 1064 nm Nd:YAG laser in the treatment of keratosis pilaris.
Conditions: Keratosis Pilaris (KP)
Interventions: Fractional carbon dioxide laser
Long-pulsed 1064 nm Nd:YAG laser

Ages Eligible for Study: Child (0-17)Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Aged 13 years old and above

Fitzpatrick skin types III or IV

Keratosis pilaris symmetrically affecting both upper outer arms

Exclusion Criteria:

Other variants and subtypes of keratosis pilaris: atrophoderma vermiculatum, erythromelanosis follicularis faciei et colli, folliculitis spinulosa decalvans, keratosis follicular spinulosa decalvans, keratosis pilaris atrophicans, keratosis pilaris atrophicans faciei, and keratosis pilaris rubra

Received any laser treatment, systemic retinoids, or dermabrasion for KP or for other indications (e.g. acne) within the past 6 months

Received topical treatment (including emollients, keratolytic agents, retinoids, or corticosteroids) for KP within the past month

Underwent hair removal by waxing, threading, or plucking in the areas to be treated within the past month

History of keloids or hypertrophic scars

Presence of other skin diseases in the area to be treated

History of autoimmune or photosensitive diseases

Intake of topical or oral photosensitizing medications

Pregnant or lactating