The goal of this clinical trial is to learn if robot-assisted lower-limb strength and gait training can improve safety, feasibility, and functional recovery in adults aged 18-60 years with lower-limb motor dysfunction due to stroke, incomplete spinal cord injury, or persistent gait impairment following orthopedic surgery. The main questions it aims to answer are:
Is robot-assisted training using the ZEPU-AI5 device safe and well-tolerated, with an acceptable rate of device-related adverse events? Does adding ZEPU-AI5-assisted training to standard-of-care rehabilitation improve functional outcomes (such as walking distance, muscle strength, balance, and mobility) compared to standard-of-care rehabilitation alone?
Researchers will compare an intervention group receiving standard-of-care rehabilitation combined with ZEPU-AI5-assisted training to a control group receiving standard-of-care rehabilitation alone, to see if the addition of robotic training leads to greater improvements in safety, functional recovery, and quality of life.
Participants will:
Undergo a baseline assessment before starting the study Receive either robot-assisted training plus standard-of-care rehabilitation, or standard-of-care rehabilitation alone, three times per week for 12 weeks Complete follow-up assessments every two weeks to evaluate safety, functional outcomes, and durability of any benefits
Inclusion Criteria:
Exclusion Criteria:
shakoorma@bmu.ac.bd+8801819410080
18 participants receiving standard-of-care rehabilitation combined with ZEPU-AI5 assisted gait training
18 participants receiving standard-of-care rehabilitation alone (including IRR and exercise)
ZEPU-AI1 Gait Robot Training Study (ZEPUAI1RCT)
ZEPU-AI3 Lower Limb Feedback Robot Training Study
ZEPU-SGI1PLUS Hand Training Study (ZEPUSGI1RCT)
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Effects of Robot-Assisted Upper Extremity Training on Cognitive and Physical Functions After Stroke