Pelvic Floor Physical Therapy and Exercise for Women With Endometriosis and Chronic Pelvic Pain | NCT07733583

NCT07733583

Overview

NCT ID: NCT07733583
Lead Sponsor: Hospital de Clinicas de Porto AlegreOTHER
Official Title: Pelvic Floor Physical Therapy and Physical Exercise Versus Placebo for the Treatment of Endometriosis With Chronic Pelvic Pain: A Randomized Controlled Trial
Brief Summary: Endometriosis is a chronic gynecological condition that can cause persistent pelvic pain, painful menstruation, painful sexual intercourse, and reduced quality of life. This study will evaluate whether specialized pelvic floor physical therapy combined with a structured physical exercise program is more effective than a placebo intervention combined with the same exercise program in reducing chronic pelvic pain in women with endometriosis. Participants will be randomly assigned to one of the two groups and followed for 12 weeks.
Conditions: Endometriosis
Chronic Pelvic Pain

Status and Timeline

Status: Recruiting
Last Update Posted: Jul 29, 2026Actual
Start Date: Mar 5, 2026Actual
Primary Completion Date: Sep 14, 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)
Sexes Eligible for Study: Female
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Female, aged 18 to 45 years.

Diagnosis of endometriosis confirmed by surgery and/or imaging examinations.

Chronic pelvic pain for at least 6 months.

Visual Analog Scale (VAS) score ≥4 for chronic pelvic pain.

Willingness and ability to provide written informed consent and comply with all study procedures.

Exclusion Criteria:

Current pregnancy or planned pregnancy during the study period.

Pelvic surgery within the previous 3 months.

Neuromodulation treatment within the previous 3 months.

Medical or musculoskeletal conditions that contraindicate participation in pelvic floor physical therapy or the exercise program.

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 64Estimated
Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Double

Contacts and Locations

Central Contacts: Priscila Peixoto da Fonseca, PT, MSc CandidateContact
ppfonseca@hcpa.edu.br

Similar Studies

Participant Group/Arms

Pelvic Floor Physical Therapy Plus Physical ExerciseExperimental

Participants assigned to this arm will receive specialized pelvic floor physical therapy combined with a structured progressive physical exercise program for 12 weeks.

Behavioral: Pelvic Floor Physical Therapy

Behavioral: Physical Exercise

Placebo Pelvic Floor Physical Therapy Plus Physical ExercisePlacebo Comparator

Participants assigned to this arm will receive a placebo pelvic floor physical therapy intervention combined with the same structured progressive physical exercise program for 12 weeks.

Behavioral: Placebo Pelvic Floor Physical Therapy