PROSPECT Registry for Individuals at Risk for Genetic Prion Disease | NCT07732608

NCT07732608

Overview

NCT ID: NCT07732608
Lead Sponsor: University Hospitals Cleveland Medical CenterOTHER
Official Title: PROSPECT: A Registry and Longitudinal Natural History Study of Individuals at Risk for Genetic Prion Disease
Brief Summary: PROSPECT is a prospective observational registry and longitudinal natural history study of adults at risk for genetic prion disease.
Conditions: Prion Diseases
Interventions: No data available

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion Criteria:

Age ≥18 years

At risk for genetic prion disease based on family history

Willing to comply with all study procedures including genetic testing and longitudinal follow-up

Resident in the United States

Sufficiently proficient in English to participate in all study procedures

Exclusion Criteria:

Lacking capacity to independently consent at time of initial enrollment

Symptomatic of prion disease at time of initial enrollment

Inability to provide a backup contact