High levels of Testosterone causes high amounts of skin bacteria (Cutibacterium Acnes) which can go into the skin during a shoulder replacement surgery and cause a terrible infection.
The goal of this experiment is to have participants take Finasteride, a medication that blocks testosterone production, for 2 weeks and evaluate the following:
Participants will:
Inclusion We will include the group most impacted by PJI
whitsa@uw.edu206-755-7847
Optimization of Skin Preparation to Reduce Cutibacterium Acnes Colonization in Superficial and Deep Samples During Prosthetic Shoulder Surgery in Male Patients
Testosterone Levels and Cutibacterium
Cutibacterium Dermal Colonization: Implications for Total Hip Arthroplasty
PROS-1-Male Hormonal Contraceptive Regimens on Prostate Tissue
The Use of Finasteride to Reduce Hematuria and Hematospermia Following TRUS Prostate Biopsy
3 Month Finasteride Challenge Test Can Significantly Improve the Performance of Screening for Prostate Cancer
On Label, Randomized, Double-Blind, Placebo-Controlled Trial of Preoperative Finasteride in Patients Undergoing Transurethral Resection of the Prostate (TURP)
Effect of Dihydrotestosterone (DHT) on Prostate Tissue [Short Title: DHT-3]