Vitamin D Status and Lipid Profile in Obese Adults With Type 2 Diabetes | NCT07729553

NCT07729553

Overview

NCT ID: NCT07729553
Lead Sponsor: Sinai UniversityOTHER
Official Title: Association Between Serum 25-Hydroxyvitamin D Status and Lipid Profile Among Obese Adults With Type 2 Diabetes Mellitus: A Cross-Sectional Study
Brief Summary: This prospective, single-center, cross-sectional observational study aims to evaluate the association between serum 25-hydroxyvitamin D concentrations and lipid profile parameters among adults with obesity and established type 2 diabetes mellitus. A total of 160 participants will be recruited from an outpatient diabetes clinic in Cairo, Egypt. Each participant will undergo a single clinical, anthropometric, and laboratory assessment. No intervention or treatment will be assigned by the investigators.
Conditions: Type 2 Diabetes Mellitus
Obesity
Dyslipidemia
Vitamin D Deficiency

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Jul 27, 2026Actual
Start Date: Jul 25, 2026Estimated
Primary Completion Date: Dec 30, 2026Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Adults aged 18 years or older.

Established diagnosis of type 2 diabetes mellitus (T2DM) according to standard diagnostic criteria.

Obesity based on body mass index (BMI) criteria.

Availability of serum 25-hydroxyvitamin D [25(OH)D] measurement.

Availability of lipid profile and glycemic laboratory parameters.

Ability and willingness to provide written informed consent.

Exclusion Criteria:

Type 1 diabetes mellitus.

Pregnancy.

Known chronic kidney disease.

Chronic liver disease.

Active malignancy.

Acute infection or inflammatory disease.

Conditions affecting gastrointestinal absorption.

Use of medications or supplements that substantially alter vitamin D metabolism (when applicable).

Study Plan

Study Type: Observational
Phase: No data available
Enrollment: 150Estimated
Primary Purpose: No data available
Allocation: No data available
Interventional Model: No data available
Masking: No data available

Contacts and Locations

Central Contacts: No data available
Locations: No data available

Similar Studies

Participant Group/Arms

Lower Vitamin D Status Group

Participants with obesity and established type 2 diabetes mellitus who have lower serum 25-hydroxyvitamin D \[25(OH)D\] concentrations according to the predefined study criteria. Vitamin D deficiency is defined as serum 25(OH)D concentration below 20 ng/mL. Participants in this group will undergo clinical and laboratory assessments, including lipid profile and glycemic measurements, to evaluate metabolic characteristics associated with lower vitamin D status.

Higher Vitamin D Status Group

Participants with obesity and established type 2 diabetes mellitus who have higher serum 25-hydroxyvitamin D \[25(OH)D\] concentrations according to the predefined study criteria. Participants in this group will undergo the same clinical and laboratory assessments, including lipid profile and glycemic measurements, for comparison with the lower vitamin D status group.