A Study of Tetanus Antibody of Healthy Adults | NCT07724379

NCT07724379

Overview

NCT ID: NCT07724379
Lead Sponsor: Peking University First HospitalOTHER
Official Title: A Prospective Study of Tetanus Antibody Protective Efficacy in Healthy Populations in Beijing
Brief Summary: The goal of this observational study is to learn about antibody level of tetanus of adults in high-income city of china. The main question it aims to answer is:

Analysis of tetanus antibody distribution across different age groups

Evaluation of the TQS method for determining antibody status

Correlation between primary vaccination history and tetanus antibody concentrations Blood samples were voluntarily provided by adult healthy participants for tetanus antibody analysis over a continuous collection period of more than one year.
Conditions: Tetanus
Interventions

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion Criteria:

Voluntarily sign the informed consent form；

Be aged 18 years or older；

Be willing to provide a blood sample for biochemical testing

Exclusion Criteria:

Receipt of immunoglobulin, blood, or blood products within 6 months prior to enrollment；

Refusal to provide tetanus vaccination history (including vaccination records, CDC vaccine administration registry, or subject's recall)；

Individuals with recent tetanus vaccination (within 5 years), acute illness, pregnancy, or immunosuppressive conditions will be excluded

Participant Group/Arms

age group

20-29;30-39;40-49;50-59;≥60

gender group

male; female

education background

high school; bachelor; master; et al

primary vaccination

≥3 doses TTCV; \< 3 doses TTCV; unknown

last TTCV dose duration

≤5 year;5-10 year; \>10 year; unkown