Designing and Implementing a Safety Net Surveillance Program for High Risk CKD | NCT07724288

NCT07724288

Overview

NCT ID: NCT07724288
Lead Sponsor: University of ManitobaOTHER
Official Title: Designing and Implementing a Safety Net Surveillance Program for High Risk CKD (CKD Safety Net)
Brief Summary: The objective of this initiative is to develop and evaluate a risk-based, provincial public health screening program for chronic kidney disease (CKD) that provides proactive care for adults at high-risk of kidney failure who have not previously been referred to a nephrologist, through risk stratification, triage, education, and follow-up.

Overall, we aim to demonstrate that an integrated risk-based provincial public health screening program for CKD is feasible, and improves identification of high-risk individuals, subsequently creating a model of care that can be adopted by other jurisdictions.
Conditions: Chronic Kidney Diseases

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Jul 24, 2026Actual
Start Date: Aug 2026Estimated
Primary Completion Date: Jun 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Age > 18 years old

Resident of Manitoba / has Manitoba Health coverage

Either:

2 eGFR <15 mL/min/1.73m2 tests within a 2-year timeframe or

A greater than 10% 2-year kidney failure risk (at 2 separate timepoints within a 2-year timeframe) - using the 4-variable or 3-variable 2-year Kidney Failure Risk Equation (KFRE)

Exclusion Criteria:

A previous billing claim from a nephrologist

Receiving palliative care within 3 months of randomization

Previous history of dialysis and/or kidney transplantation

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 972Estimated
Primary Purpose: Screening
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Single

Contacts and Locations

Central Contacts: Oksana Harasemiw, MScContact
oharasemiw@sogh.mb.ca204-632-3541

Similar Studies

Participant Group/Arms

Intervention ArmExperimental

Individuals randomized to the intervention group will receive a letter from MCHP. A follow-up reminder letter will be sent at 3 months in individuals that do not respond to the initial invitation. Individuals who respond to the letter by contacting the study team will be scheduled for an initial clinic appointment with a Clinical Assistant/Nephrologist, and will begin receiving routine clinical care thereafter, as per local clinical guidelines.

Other: Letter to participants

Control ArmNo Intervention

Individuals randomized to the control group will continue receiving usual care without any intervention from the study team. Their outcomes will be ascertained using de-identified administrative data. If the trial is successful, indivdiuals in the control group will be contacted for follow-up with a nephrologist in the same manner (i.e. through a mailout letter) as the intervention group was.