Memory Enhancement in Aging With Closed-Loop tACS | NCT07722598

NCT07722598

Overview

NCT ID: NCT07722598
Lead Sponsor: Boston University Charles River CampusOTHER
Official Title: Personalized Memory Enhancement in Aging: Pattern-Optimized tACS With Closed-Loop Precision Modulation
Brief Summary: This project optimizes high-resolution tACS to improve memory in healthy older adults, advancing drug-free approaches for ADRD. We test stimulation schedules and develop an adaptive, brain-guided tACS system to strengthen memory-supporting networks.
Conditions: Aging
Noninvasive Brain Stimulation
Memory
Interventions: Peak Frequency

Ages Eligible for Study: Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion Criteria:

65 years of age or older

normal or corrected-to-normal vision

color vision

Exclusion Criteria:

pregnant

metal implants in head

implanted electronic devices

history of neurological problems or head injury

skin sensitivity

claustrophobia

dementia (normal Montreal Cognitive Assessment > 25)

depression (normal Geriatric Depression Scale < 10)

history of psychosis

cognitive deficits (MoCA>25)

any psychoactive medication