Kinetics of C-Reactive Protein in Giant Cell Arteritis Following Glucocorticoid Initiation: A Pilot Study (GIDEON) | NCT07720804

NCT07720804

Overview

NCT ID: NCT07720804
Lead Sponsor: University Hospital, LimogesOTHER
Official Title: Kinetics of C-Reactive Protein in Giant Cell Arteritis Following Glucocorticoid Initiation: A Pilot Study
Brief Summary: We propose to analyze the kinetics of the main marker of inflammation in GCA in order to understand its links with initial clinical manifestations and the possible appearance of complications and/or relapses.

Early assessment of the rate of CRP normalization would enable us to adapt the therapeutic strategy in order to avoid complications and/or relapses.
Conditions: Giant Cell Arteritis (GCA)
Interventions: Blood tests to measure CRP

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Adult patients aged 18 or older hospitalized in the internal medicine department with a new diagnosis of ACG

Personne affiliée ou bénéficiaire d'un régime de sécurité sociale

Free and informed consent signed by the participant and the investigator

Exclusion Criteria:

Patients scheduled to be placed on a sparing regimen during hospitalization

Patients with renal insufficiency (eGFR ≤ 60 mL/min/1.73 m²)

Patients with a history of corticosteroid-treated pseudopolyarthritis

Patients with ACG and visual impairment (severity criterion)

Patients on immunosuppressants or biologic therapy

HIV infection or progressive malignancy

Known poor treatment adherence

Dementia

Pregnant or breastfeeding women

Patients under legal guardianship

Central Contacts: Kim LY, ProfessorContact
Kim.Ly@chu-limoges.fr05 55 05 05 05