Value of Ultrasound-Guided Microwave Ablation for Breast Fibroadenoma | NCT07719634

NCT07719634

Overview

NCT ID: NCT07719634
Lead Sponsor: Assiut UniversityOTHER
Official Title: Value of Ultrasound-Guided Microwave Ablation for Breast Fibroadenoma
Brief Summary: assess the efficacy of MWA in reducing fibroadenoma volume and achieving complete lesion regression at 12 months post-treatment
Conditions: Breast Fibroadenoma
Interventions: microwave ablation

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Jul 22, 2026Actual
Start Date: Aug 1, 2026Estimated
Primary Completion Date: Jun 30, 2028Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: Female
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion criteria:

Female participants ≥ 18 years

Diagnosed with fibroadenoma by clinical and ultrasonographic signs, core needle biopsy done only if atypical fibroadenoma.

Lesion(s) measurable by ultrasound (e.g., diameter 0.7 - 3.0 cm),distance from breast lesion to the skin and pectoralis muscle exceeding 10 mm and the lesion away from nipple areola area .

Symptomatic lesion or patient preference for minimally invasive treatment

Exclusion criteria:

Malignancy or high suspicion of malignancy, BIRADs 4 or more/if pathological proved.

Active infection.

Coagulopathy or contraindications to ablation.

Distance from breast lesion to the skin and pectoralis muscle less than 10 mm and the lesion near nipple areola area .

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 45Estimated
Primary Purpose: Treatment
Allocation: N/A
Interventional Model: Single Group Assignment
Masking: None (Open Label)

Contacts and Locations

Central Contacts: No data available
Locations: No data available

Similar Studies

Participant Group/Arms

breast fibroadenomaOther

Fibroadenoma is a common benign breast lesion resulting from the excess proliferation of connective tissue. Fibroadenomas characteristically contain both stromal and epithelial cells. Fibroadenomas typically occur in women between the ages of 10 and 40 years. It is the most common solid breast mass in women of all ages and the most common breast mass in the adolescent and young adult population.. The lesions are well-defined and well-circumscribed clinically, with normal overlying skin. The lesions are not fixed to the surrounding parenchyma and slide around with palpation, hence the colloquial term a breast "mouse".

Device: microwave ablation