ASPB-PIPB Combination in Cardiac Surgery | NCT07716943

NCT07716943

Overview

NCT ID: NCT07716943
Lead Sponsor: Sisli Hamidiye Etfal Training and Research HospitalOTHER
Official Title: Effects of Combined Anterior Serratus Plane and Pectoral-Intercostal Plane Blocks on Perioperative Analgesia and Enhanced Recovery After Surgery in Cardiopulmonary Bypass Surgery
Brief Summary: Cardiopulmonary bypass surgery is associated with significant postoperative pain, which may adversely affect respiratory function, delay mobilization, prolong hospital stay, and increase postoperative complications. Within Enhanced Recovery After Surgery (ERAS) protocols, multimodal analgesia and opioid-sparing strategies have become essential components of perioperative care. Ultrasound-guided fascial plane blocks, including the anterior serratus plane block (ASPB) and pectoral-intercostal plane block (PIPB), have emerged as effective and safe regional anesthesia techniques for cardiac surgery, targeting different sensory innervation of the thoracic wall. However, evidence regarding the combined use of these two blocks remains limited. This study aimed to evaluate whether the combination of ASPB and PIPB improves intraoperative and postoperative analgesia, reduces opioid consumption, and enhances postoperative recovery and ERAS outcomes compared with standard analgesic management in patients undergoing cardiopulmonary bypass surgery.

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Jul 21, 2026Actual
Start Date: Jul 1, 2026Estimated
Primary Completion Date: May 30, 2027Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion Criteria:

Patients undergoing open heart surgery via median sternotomy by the Cardiovascular Surgery Clinic

Patients over 18 years of age

ASA II-III patients

Exclusion Criteria:

- Patients undergoing emergency or recurrent surgery

Patients with left ventricular ejection fraction < 30

Patients who died per-operatively

Patients who do not provide informed consent

Presence of chronic pain

Presence of allergy to local anesthetics

Presence of infection in the area where the block will be performed

Coagulopathy

Pre-existing neurological deficit

Mental retardation

Anatomical deformity

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 60Estimated
Primary Purpose: Treatment
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: Single

Contacts and Locations

Central Contacts: MUSTAFA ALTINAYContact
m_altinay@yahoo.com05333914422

Similar Studies

Participant Group/Arms

GroupASPB + PIPB GroupExperimental

Patients in this group received ultrasound-guided bilateral anterior serratus plane block combined with bilateral pectoral-intercostal plane block after induction of general anesthesia and before surgical incision as part of the multimodal analgesia protocol.

Procedure: Combined ASPB and PIPB

ASPB Group:Active Comparator

Patients assigned to the ASPB group underwent ultrasound-guided bilateral anterior serratus plane block following induction of general anesthesia and prior to skin incision. The block was incorporated into the perioperative multimodal analgesia protocol.

Procedure: Anterior Serratus Plane Block