Inclusion Criteria:

• Both male and female.
• Participants between the age of 20-50 years old.
• Presence of calcium oxalate crystals in urine and kidneys
• The size of the stones will range from 2 to 5 mm.

Exclusion Criteria:

• People having stones of Uric acid, struvite, Cystine.
• People having any other medical condition (End stage renal disease, Chronic Kidney disease, Kidney failure, and dialysis) .
• Subjects were excluded if they were taking any medications, which might affect vitamin E metabolism (such as Wrafrin, dalteparin sodium, enoxaparin sodium).
• Pregnant and lactating females.
• People having known allergies to Vitamin E supplementation (rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing).
• Participants enrolled in other studies or taking other nutraceutical preparations.