Investigating ELSI Issues That May Facilitate or Impede Clinical Translation of Epigenetic Research. Phase 3a Survey | NCT07713667

NCT07713667

Overview

NCT ID: NCT07713667
Lead Sponsor: Washington University School of MedicineOTHER
Official Title: Investigating ELSI Issues That May Facilitate or Impede Clinical Translation of Epigenetic Research.
Brief Summary: Few people realize that environmental pollution and some behaviors like physical activity and tobacco smoking can affect their health by "turning on" or "turning off" certain genes through a process called "epigenetic modification." This study will develop and test strategies for communicating about epigenetics that are understandable and that do not increase ethical, legal or social issues (ELSI).
Conditions: Healthy
Interventions

Status and Timeline

Status: Not yet recruiting
Last Update Posted: Jul 20, 2026Actual
Start Date: Aug 1, 2026Estimated
Primary Completion Date: Oct 1, 2026Estimated
Completion Date

Participation Criteria

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: Yes
Eligibility Criteria: Inclusion Criteria:

English language speaker,

Identify as one of five racial/ethnic groups:

Non-Hispanic White

Non-Hispanic Black,

Non-Hispanic Asian

Non-Hispanic Indigenous (i.e., Alaska Native/Native Hawaiians/American Indian/Other Pacific Islander)

Hispanic (all races)

Exclusion Criteria:

Self-identify as a genetics expert

Study Plan

Study Type: Interventional
Phase: Not Applicable
Enrollment: 1,000Estimated
Primary Purpose: Other
Allocation: Randomized
Interventional Model: Parallel Assignment
Masking: None (Open Label)

Contacts and Locations

Central Contacts: Julia Maki, PhDContact
jmaki@wustl.edu314-286-2835

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Participant Group/Arms

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Uncertainty Normalization VideoExperimental

Participants will watch a brief (\<5 minute) video about the concept of Epigenetics as well as a brief (\<1 minute) video normalizing uncertainty about epigenetics research.

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