Tumor Heterogeneity of Renal Tumors Assessed by Multiparametric MRI With Direct Radiological-histopathological Correlation: an Explorative Study | NCT07713654

NCT07713654

Overview

NCT ID: NCT07713654
Lead Sponsor: University of ZurichOTHER
Official Title: Tumor Heterogeneity of Renal Tumors Assessed by Multiparametric MRI With Direct Radiological-histopathological Correlation: an Explorative Study
Brief Summary: In this study, high-resolution magnetic resonance imaging scans (MRI/mpMRI) were performed before surgical removal of the tumor and then compared with microscopic examinations of the tumor. Instead of looking at just one single area, the study compared many small, spatially correlated sections of the tumor-almost like creating a mini-map of the entire tumor.
Conditions: Kidney Cancers
Interventions: mpMRI

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers?: No
Eligibility Criteria: Inclusion criteria:

Patients with confirmed or suspected renal tumor with an approx. size of ≥ 2 cm who are scheduled for clinical MRI examination and surgical resection of the tumor

Informed consent as documented by signature (Informed Consent Form)

Patients ≥18 years of age

Exclusion criteria:

Women who are pregnant or breast feeding

Intention to become pregnant during the course of the study and lack of safe contraception

Inability to follow the procedures of the study, e.g., due to language problems, psychological disorders, dementia, etc. of the participant

Previous enrolment into the current study

Enrolment of the investigator, his/her family members, employees and other dependent persons

Patients with non-MRI compatible metallic or electronic implants, devices or metallic foreign bodies (cardiac pacemaker, shrapnel, cochlea implants, neurostimulator, or other non-MRI compatible implants).

Patients with known hypersensitivity reactions to MRI contrast agents will undergo the examination without application of a contrast agent