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This retrospective observational study aimed to compare the effects of epidural analgesia and intravenous analgesia on early postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy. Preoperative and postoperative pulmonary function tests, pain scores, opioid consumption, and intraoperative respiratory parameters were evaluated.
This retrospective observational study was conducted at Trabzon Kanuni Training and Research Hospital. Adult patients who underwent laparoscopic sleeve gastrectomy between January 2025 and October 2025 were included. Patients were divided into two groups according to postoperative analgesia technique: epidural analgesia and intravenous analgesia.
The primary outcome was postoperative change in FEV1 at 24 hours after surgery. Secondary outcomes included changes in FVC and FEV1/FVC ratio, postoperative pain scores, additional opioid consumption, and intraoperative ventilatory parameters including peak airway pressure and plateau pressure.
Demographic data, perioperative variables, pulmonary function test results, arterial blood gas analyses, and analgesia-related data were retrospectively collected from hospital records. The study was approved by the Non-Interventional Scientific Research Ethics Committee of Trabzon University Faculty of Medicine.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Epidural Analgesia | Patients who received thoracic epidural analgesia for postoperative pain management after laparoscopic sleeve gastrectomy. |
| |
| Intravenous Analgesia | Patients who received intravenous analgesia for postoperative pain management after laparoscopic sleeve gastrectomy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution) | Procedure | Thoracic epidural catheter-based analgesia using bupivacaine and fentanyl for postoperative pain management. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in FEV1 at 24 Hours After Surgery | Assessment of postoperative change in forced expiratory volume in 1 second (FEV1) measured before surgery and at postoperative 24 hours. | Preoperative period and postoperative 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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Adult obese patients undergoing laparoscopic sleeve gastrectomy at a tertiary training and research hospital.
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| Name | Affiliation | Role |
|---|---|---|
| esra kongur, M.D | Trabzon Kanuni Training and Research Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Trabzon Kanuni Training and Research Hospital | Trabzon | Turkey (Türkiye) |
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| Intravenous analgesia | Drug | Intravenous tramadol-based patient-controlled analgesia for postoperative pain management. |
|
| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D015360 | Analgesia, Epidural |
| ID | Term |
|---|---|
| D000698 | Analgesia |
| D000760 | Anesthesia and Analgesia |
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