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Emerging evidence suggests protective properties of a Mediterranean diet (MD) in relation to prevention and management of mood disorders. However, there is paucity of dietary interventions investigating adherence to MD and effects on mood and wellbeing in individuals without a clinical diagnosis. The present study aimed to investigate the effects of adherence to a short-term MD on mood and wellbeing in healthy adults
This is a 1-week, cross-over, randomised, controlled study investigating the effects of Mediterranean style diet on perceived mood and overall wellbeing in healthy adults. The intervention consists following daily for 1 week a Mediterranean style eating pattern. Participants are following their habitual diet during the control week. This is an investigator-initiated, randomised, cross-over, controlled study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A Mediterranean style diet | Active Comparator | At baseline, participants attended an Educational Group Session (EGS) introducing the principles of the Mediterranean Diet (MD), including recommended foods, foods to limit, cooking methods, and shopping tips. Participants then followed a Mediterranean-style diet for 7 days, replacing typical Western foods with MD alternatives without restricting energy intake. Practical examples and take-home materials with simple food swaps were provided to support adherence. |
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| Habitual diet | Placebo Comparator | Participants were instructed to follow their habitual diet (control) and eating practices for 7 days. without restricting energy intake. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| A mediterranean style diet | Other | At baseline, an Educational Group Session (EGS) introduced participants to the Mediterranean Diet (MD) principles to support adherence. The interactive EGS covered MD typical foods to consume and avoid, cooking methods, and practical shopping guidance. Following the EGS, participants adopted a Mediterranean-style diet for a period of 7 days. Participants were encouraged to follow the MD guidelines (replacing typical western foods with MD foods) without restricting energy intake; examples were provided during the EGS and with take-home resource materials which detailed 'simple swaps' or alternative MD food items to replace western food items. |
| Measure | Description | Time Frame |
|---|---|---|
| Mood | Change in mood measured using the Bond-Lader Visual Analogue Scale (VAS). The scale ranges from 0 to 100, with higher scores indicating a more positive mood state (better outcome). | Baseline and 7 days (final day of each condition) espressed in questionnaire scores |
| Measure | Description | Time Frame |
|---|---|---|
| Wellbeing | Change in wellbeing measured using the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS). The WEMWBS total score ranges from 14 to 70, with higher scores indicating greater mental wellbeing (better outcome). | Baseline and 7 days (final day of each condition) espressed in questionnaire scores |
| Measure | Description | Time Frame |
|---|---|---|
| Body weight | Change in body weight, measured in kilograms (kg) Change in waist circumference, measured in centimetres (cm). Lower waist circumference indicates a better outcome where reduction in central adiposity is a study objective. | Baseline and 7 days (final day of each condition) expressed in Kg |
| Physical activity |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Fotini Tsofliou | University of Roehampton | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Roehampton, School of Life and Health Sciences | London | UK | SW15 4JD | United Kingdom |
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a randomised controlled-crossover design was employed, including a washout period to reduce carryover effects. Random allocation determined participants' diet order; counterbalanced to follow the MedDiet (MD) or their habitual diet (Control) for 7 days (week 1). This was followed by a washout (week 2), before participants completed the alternate condition (week 3). This is an investigator-initiated, randomised,controlled pilot study.
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Open label
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| Habitual Diet | Other | participants were instructed to follow their habitual diet (control) and eating practices for 7 days. without restricting energy intake. |
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Change in physical activity measured using the International Physical Activity Questionnaire (IPAQ), expressed as total metabolic equivalent (MET)-minutes per week. Higher scores indicate greater physical activity levels (better outcome). The IPAQ does not have a fixed minimum or maximum score. |
| Baseline and 7 days (final day of each condition) espressed in questionnaire scores |
| Dietary intake | Change in dietary intake assessed using 7-day weighted food records collected during each 7-day intervention period. Dietary intake was quantified as daily energy and nutrient intake. There is no fixed minimum or maximum score; values are reported in their respective units (e.g., kcal/day, g/day). The direction of a better outcome depends on the specific dietary component being evaluated. | During the 7 days intervention/condition using DietPlan software |