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Photorefractive keratectomy (PRK) is a well-established surface ablation procedure for the correction of refractive errors. Despite excellent visual and refractive outcomes, postoperative pain remains a significant concern, particularly during the first few days following surgery. This pain is primarily related to corneal epithelial removal, exposure of subepithelial nerve endings, and the subsequent inflammatory response. Effective pain management is therefore essential to enhance patient comfort, improve compliance with postoperative care, and increase overall surgical satisfaction. Therefore we will compare postoperative pain levels in patients undergoing PRK using ketorolac tromethamine 0.5%-soaked bandage contact lenses versus non-medicated bandage contact lenses.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A Participants who will receive Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses | Experimental | Group A will receive ketorolac-soaked bandage contact lenses immediately after surgery. Postoperative pain will be assessed using Visual Analogue Scale at defined intervals. Epithelial healing will be monitored clinically until complete re-epithelialization. Any complications arising during postoperative period will be documented for each group. |
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| Group B Participants who will receive Non-Medicated Bandage Contact Lenses | Active Comparator | Group B will receive standard non-medicated bandage contact lenses. Postoperative pain will be assessed using Visual Analogue Scale at defined intervals. Epithelial healing will be monitored clinically until complete re-epithelialization. Any complications arising during postoperative period will be documented for each group. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses | Device | Soaking Bandage Contact Lenses in ketorolac prior to application may provide sustained drug release at the ocular surface, thereby enhancing postoperative pain control while reducing the need for repeated topical administration.Recent studies have suggested that ketorolac-soaked Bandage Contact Lenses may significantly reduce pain following Photorefractive Keratectomy without adversely affecting epithelial healing |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Pain | Postoperative pain assessed using a standardized pain scoring system (e.g., Visual Analogue Scale) at 6, 24, 48, and 72 hours postoperatively. | 72 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Epithelial Healing | Time for epithelial healing | 72 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dr Hassan Abbas, MBBS | Contact | +923076781178 | abbas.hassan97@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Madina Teaching Hospital Faisalabad | Faisalābad | Punjab Province | 38000 | Pakistan |
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|
| Contact Bandage Lenses | Device | Bandage contact lenses (BCLs) are routinely used after PRK to protect the corneal surface, reduce mechanical irritation from blinking, and promote epithelial healing |
|
| ID | Term |
|---|---|
| D012030 | Refractive Errors |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
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