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| ID | Type | Description | Link |
|---|---|---|---|
| 2024/897 | Registry Identifier | Faculty of Dentistry Research Registry |
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This clinical study aims to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar sites. Patients requiring extraction of mandibular premolars will receive immediate implant placement, with or without autogenous bone grafting, according to the study protocol.
When indicated, autogenous bone graft will be harvested using piezosurgery during the implant procedure. Participants will be followed up clinically and radiographically to assess implant stability, marginal bone level changes, and peri-implant tissue conditions over a defined follow-up period. The results of this study may help determine the effectiveness and predictability of immediate implant placement in mandibular premolar regions.
This prospective clinical study is designed to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar regions following tooth extraction. Patients indicated for extraction of mandibular premolars will be enrolled according to predefined inclusion and exclusion criteria.
Following atraumatic tooth extraction, immediate dental implant placement will be performed in the extraction socket. two group included, one without bone graft and the other group with autogenous bone graft from ramus . Autogenous bone grafting will be utilized according to the study protocol and will be harvested intraoperatively using piezosurgery to ensure precise and minimally traumatic bone collection.
Implant placement will be performed following standard surgical protocols. Primary implant stability will be assessed at the time of placement. Patients will receive postoperative care and instructions according to institutional guidelines.
Clinical and radiographic evaluations will be conducted during follow-up visits to assess implant stability, peri-implant soft tissue condition, and marginal bone level changes. Radiographic assessment will be performed using standardized imaging techniques.
The primary outcome measures will include implant stability and marginal bone level changes around the implant. Secondary outcome measures will include implant stability and marginal bone level changes around the implant . overall implant success rate.
The results of this study aim to provide evidence regarding the predictability and effectiveness of immediate implant placement in mandibular premolar sites, with particular emphasis on the role of autogenous bone graft harvested using piezosurgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Immediate implant without bone graft | Active Comparator | Immediate implant without bone graft |
|
| Immediate implant with graft | Experimental | Immediate implant with outogenous bone graft |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Immediate implant with autogenous bone graft | Procedure | Immediate implant with autogenous bone graft using piezo surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| Osseointegration success rate (%) | Implant success will be evaluated based on the absence of mobility, pain, infection, and peri-implant radiolucency around the implant. | 6 months after implant placement. |
| Measure | Description | Time Frame |
|---|---|---|
| Implant stability (ISQ) | Implant stability will be measured using resonance frequency analysis (ISQ values) at the time of implant placement and during follow-up. | At implant placement and 6 months after implant placement |
| Marginal bone loss (mm) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Suez Canal University, Faculty of Dentistry | Ismailia | 4312 | Egypt |
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| Immediate implant without bone graft | Procedure | Immediate implant without bone graft |
|
Marginal bone level changes around the implant will be assessed using standardized periapical radiographs. Measurements will be performed using Digora software
| Baseline (at implant placement) and 4 months after implant placement |
| Implant survival rate (%) | Presence of implant in situ without mobility or failure at follow-up visit. | 6 months after implant placement |
| Postoperative complication (%) | Clinical assessment of pain, swelling, infection, and delayed healing after implant placement. | Up to 6 months after implant placement. |
| ID | Term |
|---|---|
| D016388 | Tooth Loss |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D014076 | Tooth Diseases |
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| ID | Term |
|---|---|
| D016025 | Bone Transplantation |
| ID | Term |
|---|---|
| D016378 | Tissue Transplantation |
| D064987 | Cell- and Tissue-Based Therapy |
| D001691 | Biological Therapy |
| D013812 | Therapeutics |
| D019637 | Orthopedic Procedures |
| D013514 | Surgical Procedures, Operative |
| D014180 | Transplantation |
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