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This retrospective observational study evaluates the effect of different regional anesthesia techniques on perioperative blood loss in patients undergoing femoral neck fracture surgery. Patients who received tranexamic acid were grouped by anesthesia method (lumbar plexus block, spinal anesthesia, or general anesthesia). The primary outcomes were intraoperative blood loss and the change in hemoglobin between the preoperative and postoperative periods. Secondary outcomes were postoperative pain (VAS) and total analgesic consumption during the first 24 hours.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group L - Lumbar plexus block | Patients who received lumbar plexus block plus tranexamic acid. | ||
| Group S - Spinal anesthesia | Patients who received spinal anesthesia combined with tranexamic acid. | ||
| Group G - General anesthesia | Patients who received general anesthesia combined with tranexamic acid. |
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| Measure | Description | Time Frame |
|---|---|---|
| Intraoperative blood loss | Intraoperative blood loss estimated from the volume in the aspirator container and the blood absorbed in surgical sponges | Intraoperative (during surgery) |
| Change in hemoglobin level | Difference between preoperative and postoperative hemoglobin concentration (g/dL) | Preoperative and within 24 hours postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative pain score (VAS) | Postoperative pain assessed using the Visual Analog Scale (0-10) | 2, 6, 12 and 24 hours postoperatively |
| Total analgesic consumption | Total amount of analgesic consumed in the first 24 postoperative hours |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged 18-100 years who underwent femoral neck fracture surgery and received tranexamic acid, identified by retrospective chart review
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| Name | Affiliation | Role |
|---|---|---|
| Korgün Ökmen, MD | University of Health Sciences, Bursa Yüksek Ihtisas Training and Research Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bursa Yüksek Ihtisas Training and Research Hospital | Bursa | Turkey (Türkiye) |
Individual participant data will not be shared.
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| ID | Term |
|---|---|
| D005265 | Femoral Neck Fractures |
| D016063 | Blood Loss, Surgical |
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D006620 | Hip Fractures |
| D005264 | Femoral Fractures |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
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| First 24 hours postoperatively |
| D025981 |
| Hip Injuries |
| D007869 | Leg Injuries |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D007431 | Intraoperative Complications |
| D011183 | Postoperative Complications |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |