Effects of Blood Gas Perturbations

Effects of Blood Gas Perturbations on Neuromuscular Function of the Diaphragm and Lower Limbs at Rest and During Exercise.

In this study, the effects of blood gas perturbations on neuromuscular function of the diaphragm and lower limbs at rest and during exercise will be investigated.

Inclusion Criteria:

• healthy
• non.smoking
• normal lung function
• BMI: 18.5-29.9 kg/m2
• willing to adhere to study rules

Exclusion Criteria:

• Acute illness or chronic conditions of the gastrointestinal tract, and health conditions affecting metabolism, the cardiovascular or the respiratory system, or sleep
• Intake of medications affecting metabolism, the cardiovascular, the neuromuscular or the respiratory system, or sleep
• Any metal or electronics inside of the body
• Presence of cardiac pacemaker, implanted defibrillators or implanted neurostimulators
• History of seizures or epilepsy
• Tattoos on the stimulation sites
• Previous enrolment in this study
• For women: Pregnancy, breastfeeding, or intention to become pregnant during the study