Different Treatment Options For Mature Teeth With Apical Periodontitis

A Comparison Between Different Treatment Options For Mature Teeth With Apical Periodontitis: A Randomized Control Trial

A randomized control trial which aim to compare the healing potential for the following treatment options for mature teeth with apical periodontitis:

Group I: Conventional root canal treatment (CRT) Group II: Regenerative endodontic treatment (RET) using a blood clot scaffold Group III: RET using a blood clot scaffold loaded with recombinant human BMPs (rhBMPs)

Inclusion Criteria:

• Patients aged 18-30 years
• Healthy patients with no systemic diseases or known allergic reactions
• Mature permanent molars diagnosed with pulp necrosis
• Presence of a medium sized periapical lesion confirmed clinically and radiographically (PAI=3,4,5)

Exclusion Criteria:

• Patients with generalized chronic periodontitis
• Presence of small periapical lesions (PAI=1,2)
• Periodontal pockets > 3 mm
• Presence of systemic diseases or known hypersensitivity to any material used in the study