Brain-based Prediction of the Dying Duration in Humans After Withdrawal of Life Sustaining Therapies to Inform Donation After Circulatory Death

ClinicalTrials.gov ID

NCT07698262

Lead Sponsor

University of British ColumbiaOTHER

Overall Status

Not yet recruiting

Study Type

Observational

Enrollment

102Estimated

Last Update Posted

Aug 21, 2026Actual

Start Date

Jan 2027Estimated

Primary Completion Date

Dec 2030Estimated

Completion Date

Dec 2030Estimated

Official Title

Brain-based Prediction of the Dying Duration in Humans After Withdrawal of Life Sustaining Therapies to Inform Donation After Circulatory Death

Brief Summary

The purpose of this study is to develop a new tool that uses information collected before life-sustaining treatments are withdrawn to better predict whether a patient will die within the time needed for organ donation to be possible. The tool created should help improve planning for organ donation and provide families and healthcare teams with more accurate information.

• Organ Donation After Circulatory Death

Ages Eligible for Study

Adult (18-64)Older Adult (65+)

Sexes Eligible for Study

All

Accepts Healthy Volunteers

No

Eligibility Criteria

Inclusion Criteria:

1. Age ≥ 19;
2. Eligible for DCD

Exclusion Criteria:

1. Complete high cervical spinal cord injury (C5 and above)
2. Pacemaker in situ
3. Tracheostomy

Observational Model

Cohort

Time Perspective

Prospective

Lead Sponsor

University of British ColumbiaOTHER

Collaborators

Canadian Institutes of Health Research (CIHR)OTHER_GOV

denise.jaworsky@ubc.ca250-615-5088

benjamin.wierstra@interiorhealth.ca250-862-4000

Andrew.wormsbecker@fraserhealth.ca604-520-4253

anish.mitra@fraserhealth.ca(604) 581-2211

myp@mail.ubc.ca604-875-5949

Gloria.Vazquez-Grande@umanitoba.ca+1 800-432-1960

marat.slessarev@lhsc.on.ca519-685-8500

sfernando@lh.ca(613) 549-6666 ext. 6335

sdhanani@cheo.on.ca613-737-7600 ext. 3670

john.boyd@hli.ubc.ca604-682-2344 ext. 63047

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