Evaluation of Photodynamic Therapy as an Adjunct to Non-s... | NCT07697963

Studies
Evaluation of Photodynamic Therapy as an Adjunct to Non-surgical Treatment in Periodontitis in Smokers vs. Non-smokers

NCT07697963

Sponsor

University of Pristina

Status

Completed

Last Update Posted

Jul 13, 2026Actual

Enrollment

120Actual

Phase

Early Phase 1

Conditions

Periodontal Disease

Interventions

Scaling and root planing plus placebo
Photodynamic therapy (PDT)

Countries

Not provided

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Oct 2015

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jan 5, 2015Actual

Primary Completion Date

Oct 15, 2015Actual

Completion Date

Dec 15, 2015Actual

First Submitted Date

Jul 6, 2026

First Submission Date that Met QC Criteria

Jul 6, 2026

First Posted Date

Jul 13, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jul 6, 2026

Last Update Posted Date

Jul 13, 2026Actual

Description Module

Brief Summary

Patients with moderate periodontal destruction underwent mechanical debridement of the pathological changes from the periodontal pockets in one of the randomly selected quadrants and in another, also randomly selected, quadrant. In addition to non-surgical debridement, photodynamic therapy was applied. This comparison between two treatment options was evaluated between subjects who smoke and non-smokers.

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Early Phase 1

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

120Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Scaling and root planning	Active Comparator	Non-surgical treatment	Procedure: Scaling and root planing plus placebo
Photodynamic therapy	Experimental	Application of photodynamic therapy as an adjunct to non-surgical therapy	Combination Product: Photodynamic therapy (PDT)

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Scaling and root planing plus placebo	Procedure	Non-surgical treatment of periodontal pockets	Scaling and root planning

Measure	Description	Time Frame
Periodontal pocket depth reduction		6 weeks

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

at least two teeth with periodontal pockets up to 4 mm

Exclusion Criteria:

less than two teeth with periodontal pockets

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

65 Years

Standard Ages

AdultOlder Adult

Study Population

Not provided

Sampling Method

Not provided

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D010510	Periodontal Diseases

Ancestor Terms

ID	Term
D009059	Mouth Diseases
D009057	Stomatognathic Diseases

Browse Leaves

Not provided

Browse Branches

Not provided

Intervention Browse Module

MeSH Terms

ID	Term
D014080	Tooth Exfoliation
D016745	Root Planing
D010778	Photochemotherapy

Ancestor Terms

ID	Term
D009063	Dental Physiological Phenomena
D055688	Digestive System and Oral Physiological Phenomena
D012534	Dental Scaling
D003777	Dental Prophylaxis

Browse Leaves

Not provided

Browse Branches

Not provided