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This prospective observational study will evaluate postoperative hearing changes in women undergoing elective cesarean delivery under spinal anesthesia. Pure-tone audiometry will be performed before spinal anesthesia and at the predefined postoperative assessment time. The incidence, onset time, and severity of post-dural puncture headache (PDPH) will also be assessed. The study aims to determine whether hearing threshold changes occur after spinal anesthesia and whether these changes are associated with PDPH.
Spinal anesthesia is routinely used for elective cesarean delivery. Dural puncture may be associated with cerebrospinal fluid pressure changes that can affect inner-ear fluid dynamics and may result in transient changes in hearing thresholds. Post-dural puncture headache is another clinically relevant complication that may reflect cerebrospinal fluid loss and pressure changes.
Eligible women scheduled for elective cesarean delivery under spinal anesthesia will be enrolled consecutively after providing written informed consent. Spinal anesthesia will be administered according to routine clinical practice, with no additional anesthetic intervention performed for research purposes. Demographic and perioperative variables, including spinal needle gauge, sensory block level, hemodynamic measurements, vasopressor use, and occurrence of post-dural puncture headache, will be recorded. Pure-tone audiometry will be performed before surgery and at the predefined postoperative assessment time. Postoperative hearing thresholds will be compared with baseline values, and their association with post-dural puncture headache will be evaluated.
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| Measure | Description | Time Frame |
|---|---|---|
| Change in Pure-Tone Audiometry Hearing Thresholds After Spinal Anesthesia | The primary outcome is the difference between preoperative and postoperative pure-tone audiometry thresholds at the tested frequencies in each ear. Hearing thresholds will be recorded in decibels hearing level (dB HL), and the change from baseline will be analyzed | : Baseline preoperative assessment to postoperative audiometric assessment at 48 hours after spinal anesthesia |
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| Measure | Description | Time Frame |
|---|---|---|
| Association Between Hearing Threshold Changes and Post-Dural Puncture Headache | Association between postoperative changes in hearing thresholds and the occurrence of post-dural puncture headache. | Within 7 days after spinal anesthesia. |
Inclusion Criteria:
• Women aged 18 years or older.
Exclusion Criteria:
• Pre-existing hearing loss, use of hearing aids, or inability to complete audiometric testing.
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The study population will consist of pregnant women scheduled for elective cesarean delivery under spinal anesthesia at Duzce Unıversıty Medical Faculty Hospital Eligible participants will be enrolled consecutively after providing written informed consent. All participants will undergo routine spinal anesthesia as part of standard clinical care. Pure-tone audiometry will be performed preoperatively and within 48 hours postoperatively. Participants will also be followed for 7 days after spinal anesthesia for the occurrence of post-dural puncture headache.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Duzce University | Düzce | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D034381 | Hearing Loss |
| D051299 | Post-Dural Puncture Headache |
| ID | Term |
|---|---|
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012678 | Sensation Disorders |
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| D009461 |
| Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D051271 | Headache Disorders, Secondary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |