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The goal of this observational study is to evaluate nailfold capillaroscopic changes in patients with psoriasis and to assess their correlation with disease severity. The study will also explore differences in capillaroscopic findings across different clinical types of psoriasis and skin phototypes (Fitzpatrick classification). The study will include patients diagnosed with psoriasis attending dermatology outpatient clinics. Participants will undergo clinical assessment and nailfold capillaroscopy to detect microvascular changes.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nailfold Capillaroscopy | Other | Participants will undergo nailfold capillaroscopy using a USB digital capillaroscope to assess microvascular changes in psoriatic patients. Clinical assessment including PASI score and evaluation of nail involvement will also be performed. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Nailfold capillaroscopic abnormalities in psoriasis patients | Detection and description of nailfold capillaroscopic (NFC) abnormalities in patients with psoriasis. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Variation of nailfold capillaroscopic findings among different clinical types of psoriasis and correlation with disease severity (PASI score). | Correlation between PASI score and presence of NFC changes. - Comparison of nailfold capillaroscopic findings in different types of psoriasis | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
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The study will include patients clinically diagnosed with psoriasis attending the dermatology outpatient clinics at Al-Hussein and Sayed Galal University Hospitals in Cairo, Egypt during the study period.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed H Nouh, Asst Prof Derm & Venereol | Contact | +201062034079 | Dr.ahmednouh@azhar.edu.eg | |
| Hadil J Albarrawi | Contact | +201096205545 | hadeeljamil71@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Al-Hussein University Hospital & Sayed Galal University Hospital | Cairo | Egypt |
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| ID | Term |
|---|---|
| D011565 | Psoriasis |
| ID | Term |
|---|---|
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D020678 | Microscopic Angioscopy |
| D046169 | Dermoscopy |
| ID | Term |
|---|---|
| D000069416 | Intravital Microscopy |
| D008853 | Microscopy |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
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| D003933 | Diagnosis |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D008919 | Investigative Techniques |