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| Name | Class |
|---|---|
| Saudi German Hospital - Madinah | OTHER |
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The researchers are working to improve recovery after heart surgery by reducing reliance on opioids. Newer regional anesthesia techniques can provide strong pain relief with fewer risks, but the choice of method depends on each patient's condition, medications, and surgical plan
Optimal anesthesia in cardiac surgery requires careful management to avoid sympathetic stimulation, with analgesia being central to patient safety and recovery. Traditionally, high-dose opioids were used, but this approach delays extubation, conflicting with fast-track protocols that emphasize early extubation. Consequently, opioid-free analgesia has gained importance, employing regional techniques such as neuraxial, paravertebral, and fascial plane blocks.
Thoracic epidural analgesia (TEA) offers effective pain control and reduces perioperative cardiovascular and respiratory complications. However, its use in anticoagulated patients raises concern for epidural hematoma. Alternatives like paravertebral and fascial plane blocks provide comparable analgesia with lower risk. The erector spinae plane block (ESPB) reduces analgesic requirements, though deep blocks still pose bleeding risks.
Superficial plane blocks are therefore clinically valuable. The parasternal intercostal block-targeting anterior cutaneous branches of intercostal nerves-has emerged as a safe option for patients undergoing median sternotomy while on anticoagulant or antiplatelet therapy. Additionally, bilateral rectus sheath block can reduce chest tube insertion pain after cardiac surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Parasternal/ Rectus sheath | Experimental | Patients will receive Parasternal and rectus sheath blocks; with injection of 10 ml bupivacaine 0.25% in each side after confirmation of needle position. Both parasternal and rectus heath blocks will be performed bilaterally |
|
| Erector Spinae Plane Block | Experimental | The patients will receive a bilateral ESPB with an injection of 20 ml of bupivacaine 0.25%. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Parasternal/ Rectus sheath block | Procedure | the parasternal block will be performed parasternally at the level of fifth rib to the plane between the pectoralis major and the internal intercostal muscle. The rectus sheath block will be performed through injection in the plane posterior to the rectus abdominis muscle and anterior to the posterior rectus sheath |
| Measure | Description | Time Frame |
|---|---|---|
| Numeric rating score | postoperative pain scores using Numerical Rating Scale (NRS) | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative opioid consumption | opioid consumption in the first 24 hours postoperatively | 24 hours |
| extubation time | time to extubate |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Walaa Y Elsabeeny, MD | Contact | 01007798466 | walaa.elsabeeny@nci.cu.edu.eg | |
| Mostafa A Ibrahim, MD | Contact | +966541227090 | MAbIbrahim@sghgroup.net |
| Name | Affiliation | Role |
|---|---|---|
| Walaa Y Elsabeeny, MD | A Professor of Anesthesia, Critical Care and Pain Management, National Cancer Institute, Cairo University | Principal Investigator |
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| ID | Term |
|---|---|
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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| Erector spinae plane block | Procedure | injection above the transverse process |
|
| immediate postoperative |
| first time to request analgesia | first time to request opioid analgesia | 24 hours |
| peri-operative hemodynamics | incidence of hypotension, hypertension, tachycardia and bradycardia | intraoperative and 24 hours |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |