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| ID | Type | Description | Link |
|---|---|---|---|
| 4R00EY036497-03 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Eye Institute (NEI) | NIH |
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In this experiment, subjects will view shapes on a screen with varying colors and be asked to focus their eyes on the shapes. The shapes will look as though they are jumping to random distances away from the eye. As the subjects focus their eyes on the shapes, the investigators will measure the focus of their eyes using a device called a wavefront sensor. This device uses infrared light to measure the optical properties of the eye in real time. Our goal is to find out how well the eye focuses on different colors. Our broad goal is to better understand how the eye focuses because that process is a major part of having clear and good vision.
In this experiment, subjects will view Gabor patterns on a display through a Badal relay. The Gabor patterns will vary in their color. The colors will be picked to selectively modulate cone photoreceptor activity in different directions in cone contrast space. Subjects will be instructed to accommodate to the patterns while the virtual distance of the screen is manipulated with a focus-adjustable lens. As they do so, the investigators will measure the wavefronts of their eyes using a Shack-Hartmann wavefront sensor.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Color variation in visual stimulus | Experimental | Each participant undergoes all experimental conditions, in a within-subjects design. Each intervention corresponds to a different stimulus color. The 4 colors are: 1) grayscale (L, M, and S-cone modulation), 2) L and S cone modulation only, 3) L and M cone modulation only, and 4) M and S cone modulation only. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Color | Other | Each intervention involves showing a participant a stimulus with a particular color on a screen display, and asking the participant to focus their eyes on the stimulus. The 4 colors are: 1) grayscale (L, M, and S-cone modulation), 2) L and S cone modulation only, 3) L and M cone modulation only, and 4) M and S cone modulation only. |
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy of ocular accommodation | Ocular accommodation is the focusing response of the lens in the eye. When the stimulus viewed by the participant changes in distance, the eye automatically refocuses. The investigators measure this refocusing using a device called a wavefront sensor. The investigators are particularly interested in how accurate this refocusing is, which is measured in units of diopters. | Each measurement takes 3 seconds. In the experiment, there will be two sessions, each lasting approximately 1 hour, on separate days. In each session, a total of 420 measurements will be taken. |
| Speed of ocular accommodation | The investigators are interested in how quickly the eye refocuses when a near object moves farther away. Typically, this process takes around 1 second, but it can take longer or shorter depending on the individual and on the object being viewed. By analyzing data collected by the wavefront sensor, the investigators will calculate how long it took for the eye to refocus during each measurement. | Each measurement takes 3 seconds. In the experiment, the investigators will take measurements over the course of two sessions, each on separate days and lasting approximately 1 hour. During each session, 420 measurements will be collected. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Benjamin M Chin, Doctorate | Contact | 8454534320 | bmccis@rit.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chester F. Carlson Center for Imaging Science | Rochester | New York | 14623 | United States |
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| ID | Term |
|---|---|
| D003116 | Color |
| ID | Term |
|---|---|
| D008027 | Light |
| D055620 | Optical Phenomena |
| D055585 | Physical Phenomena |
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