Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Chronic post-surgical pain (CPSP) remains a common complication after thoracic surgery and may significantly impair patients' quality of life. Although the widespread adoption of video-assisted thoracic surgery (VATS) has reduced surgical trauma and improved postoperative recovery, a substantial proportion of patients still develop persistent pain.
The EVATHO study is a multicenter prospective observational cohort designed to determine the prevalence of CPSP three months after VATS and to identify perioperative factors associated with its development. Adult patients undergoing thoracic surgery by VATS at Montpellier and Nice University Hospitals will be prospectively enrolled.
Pain intensity, neuropathic pain characteristics, anxiety, depression, quality of life, and analgesic consumption will be assessed using validated questionnaires during the perioperative period and at 1 and 3 months after surgery. The results of this study may help identify patients at increased risk of CPSP and improve perioperative pain management strategies following thoracic surgery.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with chronic post-surgical pain | Chronic post-surgical pain defined as a Brief Pain Inventory (BPI) average pain score greater than 3 at the 3-month postoperative follow-up. | 3 months after surgery. |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative pain at 1 month after VATS | Post-surgical pain defined as a Brief Pain Inventory (BPI) average pain score greater than 3 at the 1-month postoperative follow-up. | 1 month after thoracic surgery |
| Visual Analogue Scale (VAS) pain score |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Adult patients undergoing video-assisted thoracic surgery (VATS) for pulmonary resection, pleural procedures, chest wall surgery, or lung biopsy at Montpellier and Nice University Hospitals.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Benjamin Bourdois, MD | Contact | +33467335958 | b-bourdois@chu-montpellier.fr | |
| Sophie Bringuier, MD | Contact | +33467335958 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Pain intensity measured using the Visual Analogue Scale (VAS), with scores ranging from 0 (no pain) to 10 (worst imaginable pain).
| Preoperative assessment, postoperative day 1, postoperative day 2, 1 month, and 3 months after surgery. |
| Cumulative postoperative opioid consumption. | Total opioid consumption during the postoperative period as morphine milligram equivalents | Postoperative day 1, postoperative day 2, 1 month, and 3 months after surgery. |
| Douleur Neuropathie 4 (DN4) score | Neuropathic pain measured using the Douleur Neuropathique 4 (DN4) questionnaire. Scores range from 0 to 10, with scores greater than or equal to 4 indicating neuropathic pain. | Preoperative assessment, postoperative day 1, postoperative day 2, 1 month, and 3 months after surgery. |
| Hospitalier Anxiety and depression Scale (HADS) anxiety score | Anxiety measured using the hospital Anxiety and Depression Scale (HADS-A). Scores range from 0 to 21, with scores greater than or equal to 11 indicating clinically significant anxiety. | Preoperative assessment, 1 month, and 3 months after surgery. |
| Hospital Anxiety and Depression Scale (HADS) depression score | Depression measured using the Hospital Anxiety and Depression Scale (HADS-D). Scores range from 0 to 21, with scores greater than or equal to 11 indicating clinically significant depression. | Preoperative assessment, 1 month, and 3 months after surgery |
| Brief Pain Inventory (BPI) pain interference score | Pain interference with daily activities measured using the Brief Pain Inventory (BPI) interference subscale | 1 month and 3 months after surgery. |
| Short Form-12 Physical component summary score | Physical health-related quality of life measured using the Physical Component Summary (PCS) score of the Short Form-12 (SF-12) questionnaire. | Preoperative assessment, 1 month, and 3 months after surgery. |
| Short form-12 Mental Component Summary score | Mental health-related quality of life measured using the Mental Component Summary (MCS) score of the Short Form-12 (SF-12) questionnaire. | Preoperative assessment, 1 month and 3 months after surgery |
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| D009437 | Neuralgia |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
Not provided
Not provided