LIFU for Chronic Pain and Generalized Anxiety Disorder | NCT07686354 | Trialant

LIFU for Chronic Pain and Generalized Anxiety Disorder | NCT07686354 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Low-intensity focused ultrasound for neuromodulation	Experimental	Accelerated (repeat) LIFU application for neuromodulation	Device: Low Intensity Focused Ultrasound

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Low Intensity Focused Ultrasound	Device	Low-Intensity Focused Ultrasound applied multiple times in a single study visit.	Low-intensity focused ultrasound for neuromodulation

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Safety - monitoring of possible symptoms	Symptom monitoring before and after LIFU applications and throughout 6 months of follow-up. Each symptom is presented with a likert scale (absent, mild, moderate, severe) - along with a free response option for any symptoms not included in the list.	Throughout study participation at multiple time points, approximately 6 months.
Changes in Chronic Pain - self report	Participants will complete the Brief Pain Inventory (BPI) at multiple time points throughout the 6 month period. This questionnaire asks participants to rate their pain on a 10 point scale (10 being the most pain).	Multiple timepoints throughout the 6 month experimental timeframe.
Changes in Anxiety - self report	Participants will complete the Beck Anxiety Inventory (BAI) at multiple time points before and after LIFU application to track changes in anxiety throughout the 6 month timeframe. The BAI probes different symptoms of anxiety and participants rate it on a likert scale (not at all, mildly, moderately, or severely).	Throughout the experimental timeframe, approximately 6 months.

Contacts/Locations Module

Condition Browse Module