Nd:YAG Laser Combined With Injection Sclerotherapy Versus Diode Laser in the Treatment of Reticular Veins and Telangiectasias Using CLaCS Technique

Comparative Study Between Nd:YAG Laser Combined With Injection Sclerotherapy Versus Diode Laser in the Treatment of Reticular Veins and Telangiectasias Using CLaCS Technique

This study aims to compare the efficacy (in terms of vein clearance) and safety of Nd:YAG laser combined with injection sclerotherapy versus diode laser combined with injection sclerotherapy in the treatment of reticular veins and telangiectasias using the Cryo-Laser and Cryo-Sclerotherapy (CLaCS) technique.

Reticular veins and telangiectasias (spider veins) represent common chronic venous disorders affecting a large proportion of the adult population, particularly women.

The Cryo-Laser and Cryo-Sclerotherapy (CLaCS) technique has emerged as an innovative method combining transdermal laser therapy, injection sclerotherapy, and skin cooling. This multimodal approach enhances visualization of feeder veins using augmented reality or vein illumination systems, allowing precise targeting and improved clearance rates. Cooling reduces pain and protects the epidermis, making the procedure more tolerable and safer.

Nd:YAG laser (1064 nm) is considered the cornerstone of the CLaCS technique due to its deeper penetration and selective photothermolysis of hemoglobin. It effectively targets deeper reticular veins (up to 3-4 mm depth), induces vessel wall contraction, and facilitates subsequent sclerotherapy.

Inclusion Criteria:

• Patients aged 18-60 years.
• Both sexes.
• Presence of reticular veins and/or telangiectasias (CEAP classification C1).
• Fitzpatrick skin types II-V.
• Patients seeking cosmetic treatment.

Exclusion Criteria:

• Pregnancy or lactation.
• History of deep vein thrombosis.
• Coagulation disorders.
• Allergy to sclerosant agents.
• Active skin infection at treatment site.
• Previous treatment of target veins within 6 months.
• Great saphenous vein or short saphenous vein incompetence.
• Deep venous insufficiency or thrombosis.
• Abnormal venous duplex findings.