PregnAncy-Related Aortic DISsEction in China

ClinicalTrials.gov ID

NCT07672210

Lead Sponsor

DeltaHealth Hospital · ShanghaiOTHER

Overall Status

Recruiting

Study Type

Observational

Enrollment

500Estimated

Last Update Posted

Jul 17, 2026Actual

Start Date

Mar 17, 2026Actual

Primary Completion Date

Nov 2, 2026Estimated

Completion Date

Apr 16, 2027Estimated

Official Title

PregnAncy-Related Aortic DISsEction in China: A Multicenter National Registry

Brief Summary

A multicenter observational study on pregnancy-related aortic dissection

• Pregnancy Complication
• Aortic Dissection
• Marfan Syndrome
• Loeys-Dietz Syndrome
• Vascular Ehlers-Danlos Syndrome
• Maternal and Neonatal Outcomes

• Intervention strategies including medication or surgery

Ages Eligible for Study

Child (0-17)Adult (18-64)

Sexes Eligible for Study

Female

Accepts Healthy Volunteers

No

Eligibility Criteria

Inclusion Criteria:

• Aortic dissection is diagnosed based on symptoms and physical findings, and confirmed by computed tomographic angiography (CTA) and/or transthoracic echocardiography
• Aortic dissection occurring during pregnancy or within 12 weeks postpartum

Exclusion Criteria:

• Previous history of aortic dissection, but no new aortic dissection occurring during pregnancy or within 12 weeks postpartum

Observational Model

Cohort

Time Perspective

Retrospective

Lead Sponsor

DeltaHealth Hospital · ShanghaiOTHER

Collaborators

The Second Affiliated Hospital of Hainan Medical UniversityOTHER

Beijing Anzhen HospitalOTHER

West China HospitalOTHER

Xiangya Hospital of Central South UniversityOTHER

Second Xiangya Hospital of Central South UniversityOTHER

Sichuan Provincial People's HospitalOTHER

Yantai Yuhuangding HospitalOTHER

First Hospital of China Medical UniversityOTHER

First Affiliated Hospital Xi'an Jiaotong UniversityOTHER

Qinghai Red Cross HospitalOTHER

Shanxi Bethune HospitalOTHER

Shandong Provincial HospitalOTHER_GOV

Shengjing HospitalOTHER

Zhejiang Provincial People's HospitalOTHER

Ningbo Medical Center Lihuili HospitalOTHER_GOV

Central China Fuwai Hospital of Zhengzhou UniversityOTHER

Xiamen Cardiovascular Hospital, Xiamen UniversityOTHER

Linfen Central HospitalOTHER

Shenzhen Sun Yat-sen Cardiovascular HospitalOTHER

The Affiliated Hospital Of Guizhou Medical UniversityOTHER

The University of Hong Kong-Shenzhen HospitalOTHER

Hebei Medical University Fourth HospitalOTHER

Second Affiliated Hospital of Nanchang UniversityOTHER

Southwest Hospital, ChinaOTHER

Gulou Hospital Affiliated to Medical College of Nanjing UniversityUNKNOWN

The Second Hospital of Shandong UniversityOTHER

First Affiliated Hospital, Sun Yat-Sen UniversityOTHER

First Affiliated Hospital of Gannan Medical UniversityOTHER

The First Affiliated Hospital of Zhengzhou UniversityOTHER

LanZhou UniversityOTHER

Peking Union Medical College HospitalOTHER

First Affiliated Hospital of Harbin Medical UniversityOTHER

The First Hospital of Jilin UniversityOTHER

The Fourth Affiliated Hospital of Zhejiang University School of MedicineOTHER

RenJi HospitalOTHER

Peking University People's HospitalOTHER

The First Affiliated Hospital of Guangzhou Medical UniversityOTHER

Henan Provincial Chest HospitalOTHER

First Affiliated Hospital of Wenzhou Medical UniversityOTHER

Shanghai Zhongshan HospitalOTHER

Qilu Hospital of Shandong UniversityOTHER

The First Affiliated Hospital of Bengbu Medical UniversityOTHER

Wannan Medical College Yijishan HospitalOTHER

Anhui Provincial HospitalOTHER_GOV

Shanxi Yuncheng Central HospitalUNKNOWN

Liuzhou Workers' HospitalOTHER_GOV

The Third People's Hospital of ChengduOTHER

Suining Central HospitalOTHER

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER

Wuhan TongJi HospitalOTHER

Renmin Hospital of Wuhan UniversityOTHER

The General Hospital of Southern Theater CommandOTHER

Xijing Hospital，FMMUUNKNOWN

Zunyi Medical CollegeOTHER

The Affiliated Hospital of Qingdao UniversityOTHER

Shanghai Chest Hospital of Shanghai Jiao Tong UniversityOTHER

The First Affiliated Hospital of Anhui Medical UniversityOTHER

The People's Hospital of GaozhouOTHER

The Second Hospital of Nanjing Medical UniversityOTHER

Nanjing First Hospital, Nanjing Medical UniversityOTHER

General Hospital of Ningxia Medical UniversityOTHER

Guangdong Provincial People's HospitalOTHER

Yan'an Affiliated Hospital of Kunming Medical UniversityOTHER

Second Affiliated Hospital of Zhengzhou UniversityOTHER

Henan Provincial People's HospitalOTHER

Wuhan Asia Heart HospitalOTHER

Changhai HospitalOTHER

Taihe Hospital affiliated to Hubei University of MedicineUNKNOWN

Zhongnan HospitalOTHER

Luoyang Central HospitalOTHER

People's Hospital of Xinjiang Uygur Autonomous RegionOTHER

Qingdao Municipal HospitalOTHER

The First Affiliated Hospital of Nanchang UniversityOTHER

Hainan General HospitalOTHER

The First Hospital of Hebei Medical UniversityOTHER

Gansu Provincial HospitalOTHER

The First Affiliated Hospital of Shanxi Medical UniversityOTHER

First Affiliated Hospital of Guangxi Medical UniversityOTHER

First Affiliated Hospital of Ningbo UniversityNETWORK

Fujian Medical University Union HospitalOTHER

Huai'an First People's HospitalOTHER

Chinese University of Hong KongOTHER

Yichang Central People's HospitalOTHER

Zhongshan People's Hospital, Guangdong, ChinaOTHER

Shiyan City Renmin HospitalOTHER_GOV

The First Affiliated Hospital of Dalian Medical UniversityOTHER

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